I like SOHO and Greenwich Village. Plenty of cool little restaurants but do a big web search for clubs and all that cause NYC is SUPER SONIC EXPENSIVE (as you know), totally out of control !! For hotel info (good prices - for Manhattan - in small little clean and cool hotels) go on -
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www.eurocheapo.com]
They cover almost all of Europe's big cities and ONLY do NYC in the USA cause I think most of the team/crew are from NYC so it's easy for them to add it in (plus it's almost impossible to find a cool little hotel - the kind you can find all over Europe - without paying a fortune) GREAT website, Fantastic !!!
Remember, half price tickets for Broadway plays/shows at TKTS in Times Square (it used to be around 3 pm back in the day when I used to go to NYC all the time before they turned into some strange Disneyland NYC - 80's/early 90's) - on the day of the show. I'd use buses and taxis and feet, would avoid the subway (for many and obvious reasons)
Statue of Liberty is great. Wonderful gift from France. Ellis Island - Island where all the immigrants came through/were processed - is also interesting (my parents names are on the "Wall of Immigrants" which I find quite nice (I'm sure they would be happy) Have fun, David Bowie lives around SOHO/TRIBECA, maybe you'll bump into him. I hear he walks around down there a lot. Le Mind