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bleedingman
New data suggests Pfizer and Moderna's vaccines may be less effective against Delta
Overall, it found that the Moderna vaccine was 86% effective against infection over the study period, and Pfizer's was 76%. Moderna's vaccine was 92% effective against hospitalization and Pfizer's was 85%.
But the vaccines' effectiveness against infection dropped sharply in July, when the Delta variant's prevalence in Minnesota had risen to over 70%.
Moderna was 76% effective against infection, and Pfizer was only 42% effective.
The study found similar results in other states. For example, in Florida, the risk of infection in July for people fully vaccinated with Moderna was about 60% lower than for people fully vaccinated with Pfizer.
Why it matters: Although it has yet to be peer-reviewed, the study raises serious questions about both vaccines' long-term effectiveness, particularly Pfizer's.
It's unclear whether the results signify a reduction in effectiveness over time, a reduced effectiveness against Delta, or a combination of both.
"Based on the data that we have so far, it is a combination of both factors," said Venky Soundararajan, a lead author of the study. "The Moderna vaccine is likely — very likely — more effective than the Pfizer vaccine in areas where Delta is the dominant strain, and the Pfizer vaccine appears to have a lower durability of effectiveness.”
He added that his team is working on a follow-up study that will try to differentiate between the durability of the two vaccines and their effectiveness against Delta.
Yes, but: There has been no data so far that has found either vaccine's protection against severe disease and death is significantly less against Delta, and the study notes that there doesn't appear to be much of a difference in complications stemming from breakthrough infections based on which vaccine someone got.
And experts cautioned against rushing to conclusions.
“This is the kind of surprising finding that needs confirmation before we should accept its validity," said Cornell virologist John Moore.
Between the lines: The two shots both use mRNA, but there are significant differences between them.
For example, Moderna is given in a stronger dose than Pfizer, and there is a slightly different time interval between shots.
"There are a few differences between what are known to be similar vaccines .... None of these variables is an obvious smoking gun, although the dosing amount seems the most likely to be a factor," Moore said.
In a statement, Pfizer said it and BioNTech "expect to be able to develop and produce a tailor-made vaccine against that variant in approximately 100 days after a decision to do so, subject to regulatory approval.
[news.yahoo.com]
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TheGreek
Stevie Nicks gets it huh
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The SicilianQuote
TheGreek
Stevie Nicks gets it huh
Have you heard the story about the Zen Master and the Little Boy?
The boy’s father bought him a horse for his fourteenth birthday and everyone in the village said, “Isn’t that wonderful, the boy got a horse?” and the Zen Master said, “We’ll see.”
A couple of years later the boy fell from his horse, badly breaking his leg and everyone in the village said, “How awful, he won’t be able to walk properly.” The Zen Master said, “We’ll see.”
Then, a war broke out and all the young men had to go and fight, but this young man couldn’t because his leg was still messed up and everyone said, “How wonderful!” The Zen Master said, “We’ll see.”
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daspyknowsQuote
The SicilianQuote
TheGreek
Stevie Nicks gets it huh
Have you heard the story about the Zen Master and the Little Boy?
The boy’s father bought him a horse for his fourteenth birthday and everyone in the village said, “Isn’t that wonderful, the boy got a horse?” and the Zen Master said, “We’ll see.”
A couple of years later the boy fell from his horse, badly breaking his leg and everyone in the village said, “How awful, he won’t be able to walk properly.” The Zen Master said, “We’ll see.”
Then, a war broke out and all the young men had to go and fight, but this young man couldn’t because his leg was still messed up and everyone said, “How wonderful!” The Zen Master said, “We’ll see.”
huh?
Yes she gets it. She doesn't want to get sick from Covid and doesn't want her fans to either. The opposite of Eric Clapton.
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The SicilianQuote
TheGreek
Stevie Nicks gets it huh
Have you heard the story about the Zen Master and the Little Boy?
The boy’s father bought him a horse for his fourteenth birthday and everyone in the village said, “Isn’t that wonderful, the boy got a horse?” and the Zen Master said, “We’ll see.”
A couple of years later the boy fell from his horse, badly breaking his leg and everyone in the village said, “How awful, he won’t be able to walk properly.” The Zen Master said, “We’ll see.”
Then, a war broke out and all the young men had to go and fight, but this young man couldn’t because his leg was still messed up and everyone said, “How wonderful!” The Zen Master said, “We’ll see.”
Exactly what I meant that she gets the severity of the COVID-19 Pandemic which is now raging in it's fourth wave here in the USA . i applaud her very wise desicion to stay healthy versus another mega payday from a tour that might happen or wont happen . Quality of life for me is far more important than anything else and as the old adage goes "this to shall pass" You certainly know from reading my comments what side I fall on (safety above all else )Quote
daspyknowsQuote
The SicilianQuote
TheGreek
Stevie Nicks gets it huh
Have you heard the story about the Zen Master and the Little Boy?
The boy’s father bought him a horse for his fourteenth birthday and everyone in the village said, “Isn’t that wonderful, the boy got a horse?” and the Zen Master said, “We’ll see.”
A couple of years later the boy fell from his horse, badly breaking his leg and everyone in the village said, “How awful, he won’t be able to walk properly.” The Zen Master said, “We’ll see.”
Then, a war broke out and all the young men had to go and fight, but this young man couldn’t because his leg was still messed up and everyone said, “How wonderful!” The Zen Master said, “We’ll see.”
huh?
Yes she gets it. She doesn't want to get sick from Covid and doesn't want her fans to either. The opposite of Eric Clapton.
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Rocknroll1969
2021 is looking like 2020 all over again despite the vaccines. I found the Axios news story very concerning. The company I work for was looking to put us back in the office the week of Sept 6. Now they are pushing it back to November.
Indeed! The forth wave of the virus is rising. The number of infections is rising fast, more and more young persons in hospitals, the number of vaccined people is rising too slow. Time enough for the virus to create new mutations - Delta has arrived, others will follow. Crazy people are telling dangerous rubbish about Covid ignoring the facts. That's the mix.Quote
bv
The pandemic is not over yet.
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The Sicilian
BV, could you wait a day or two before merging new topic threads into threads with nearly 300 pages. It is of a different topic. The topic is easily lost for those who have not read it yet. Many bypass the topic because it seems redundant. Thanks.
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bye bye johnny
AEG Presents to Require Proof of Vaccination for Ticketholders and Crew at All U.S. Venues
By Chris Willman
August 12,2021
In one of the strongest statements yet made by a major player in support of a pro-vaccination policy in the live music industry, AEG Presents, the second-largest live company in the country, has announced that proof of vaccination will be required going forward for ticketholders and crew at all the venues it owns or operates in the United States.
“We have come to the conclusion that, as a market leader, it was up to us to take a real stand on vaccination status,” said Jay Marciano, COO of AEG and chairman-CEO of AEG Presents, in a statement. “Just a few weeks ago, we were optimistic about where our business, and country, were heading. The Delta variant, combined with vaccine hesitancy, is pushing us in the wrong direction again. We realize that some people might look at this as a dramatic step, but it’s the right one. We also are aware that there might be some initial pushback, but I’m confident and hopeful that, at the end of the day, we will be on the right side of history and doing what’s best for artists, fans, and live event workers.”
Added Marciano, “Our hope is that our pro-active stance encourages people to do the right thing and get vaccinated,” added Marciano. “We’ve already had to deliver bad news about JazzFest this week; I think everyone can agree that we don’t want concerts to go away again, and this is the best way to keep that from happening.”
The list of affected venues includes the Roxy and El Rey in Los Angeles, Webster Hall and Brooklyn Steel in New York and the Theatre at Resorts World Las Vegas. A number of festivals also fall under the AEG aegis — many of which have already been canceled for this year — include Coachella, Firefly, Day N Vegas, the just-nixed New Orleans Jazz & Heritage Festival.
AEG says the policy will be in full effect by Oct. 1. Up till that date, either proof of vaccination or a negative COVID test within 72 hours will be allowable for entry. “The date was chosen specifically to allow time for any eligible unvaccinated ticketholders and staff to reach fully vaccinated status should they choose to do so,” the statement said.
“Certain states’ regulations may override our mandate,” noted Shawn Trell, COO and general counsel of AEG Presents said, “or a few artists may not want to immediately get on board with the plan, but we know that using our platform to take a strong position on vaccinations can make an impact. The message we want to send is simple and clear: the only way to be as safe as possible is to require everyone to be vaccinated. And we’re confident that others who haven’t been ready to make this full commitment yet will follow our lead.”
Live Nation, the top live music company, has a less strict policy as of now, having announced that proof of vaccination or a recent COVID test will be required for select shows, with individual artists’ discretion a factor.
[variety.com]